| Leipzig Karlsruher Straße | |
| Native Name Lang: | de |
| Symbol: | s |
| Symbol Location: | mitteldeutschland |
| Type: | Hp |
| Borough: | Leipzig, Saxony |
| Country: | Germany |
| Coordinates: | 51.3172°N 12.2792°W |
| Platforms: | 2 |
| Zone: | MDV 110[1] |
| Electrified: | at opening |
| Former: | 1983-1991 Leipzig Ho-Chi-Minh-Straße |
Leipzig Karlsruher Straße (German: Haltepunkt Leipzig Karlsruher Straße) is a railway station located in Leipzig, Germany. The station opened in June 1983 and was closed between April 2011 and 15 December 2013. The station is located on the Leipzig-Plagwitz–Leipzig Miltitzer Allee railway. The train services are operated by Deutsche Bahn, as part of the S-Bahn Mitteldeutschland.