Leiorreuma is a genus of script lichens in the family Graphidaceae. It has 18 species. The genus was circumscribed by Franz Gerhard Eschweiler in 1824, with Leiorreuma hepaticum assigned as the type species.
Leiorreuma is identified by certain features. It has apothecia with noticeable opened . The is often thin on the sides but well-developed at the base and appears . The hymenium is dotted with small specks, and the spores are pale brown and have thin walls with crosswise septa or are divided into many compartments . They are not stained by iodine.