| Leine | |
| Mouth Location: | Helme |
| Mouth Coordinates: | 51.4561°N 11.1282°W |
| Subdivision Type1: | Country |
| Subdivision Name1: | Germany |
| Subdivision Type2: | States |
| Subdivision Name2: | Saxony-Anhalt |
Leine is a river of Saxony-Anhalt, Germany. It flows into the Helme in Bennungen.