| Leine | |
| Mouth Coordinates: | 51.6583°N 11.3561°W |
| Progression: | Eine→ |
| Subdivision Type1: | Country |
| Subdivision Name1: | Germany |
| Subdivision Type2: | States |
| Subdivision Name2: | Saxony-Anhalt |
Leine is a river of Saxony-Anhalt, Germany. It flows into the Eine in Stangerode.