| Lefty Willis | |
| Position: | Pitcher |
| Bats: | Left |
| Throws: | Left |
| Birth Date: | 4 November 1905 |
| Birth Place: | Leetown, West Virginia |
| Death Place: | Bethesda, Maryland |
| Debutleague: | MLB |
| Debutdate: | October 3 |
| Debutteam: | Philadelphia Athletics |
| Finalleague: | MLB |
| Finaldate: | July 12 |
| Finalteam: | Philadelphia Athletics |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 3-1 |
| Stat2label: | Earned run average |
| Stat2value: | 3.92 |
| Stat3label: | Strikeouts |
| Stat3value: | 23 |
| Teams: | |
Charles William "Lefty" Willis (November 4, 1905 – May 10, 1962) was a Major League Baseball pitcher who played from to with the Philadelphia Athletics.