| Competition: | League of Ireland |
| Season: | 1951–52 |
| Winners: | St Patrick's Athletic (1st title) |
| Matches: | 132 |
| Total Goals: | 521 |
| League Topscorer: | Shay Gibbons (26 goals) |
| Biggest Home Win: | Dundalk 6–0 Limerick Shamrock Rovers 6–0 Sligo Rovers Sligo Rovers 6–0 Limerick |
| Biggest Away Win: | Bohemians 1–5 St Patrick's Athletic |
| Highest Scoring: | Shelbourne 4–4 Drumcondra Shelbourne 6–2 Sligo Rovers Sligo Rovers 4–4 Shelbourne Waterford 2–6 Transport |
| Prevseason: | 1950–51 |
| Nextseason: | 1952–53 |
The 1951–52 League of Ireland was the 31st season of senior football in the Republic of Ireland.
Cork Athletic were the two-time defending champions.
Two new teams were elected to the League: Evergreen United and St Patrick's Athletic.
St Patrick's Athletic won their first title.
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 | Shay Gibbons | St Patrick's Athletic | 26 |
| 2 | Rory Dwyer | Shelbourne | 22 |
| 3 | Dessie Glynn | Drumcondra | 20 |
| 4 | Billy Burns | Shamrock Rovers | 15 |
| Seán McCarthy | Evergreen United | ||
| 6 | Jack Fitzgerald | Waterford | 14 |
| 7 | Joey Dunne | Bohemians | 12 |
| 8 | Liam Coll | Sligo Rovers | 11 |
| Bernie Lester | Transport | ||
| 10 | Johnny Armstrong | Sligo Rovers | 10 |
| Jimmy Nelson | Waterford | ||
| Johnny Vaughan | Cork Athletic | ||