| Competition: | League of Ireland |
| Season: | 1943–44 |
| Winners: | Shelbourne (4th title) |
| League Topscorer: | Seán McCarthy (16 goals) |
| Biggest Home Win: | Shamrock Rovers 7–0 St James's Gate |
| Biggest Away Win: | St James's Gate 0–7 Cork United |
| Highest Scoring: | Cork United 6–3 Drumcondra |
| Matches: | 56 |
| Total Goals: | 222 |
| Prevseason: | 1942–43 |
| Nextseason: | 1944–45 |
The 1943–44 League of Ireland was the 23rd season of senior football in the Republic of Ireland. Cork United were the two-time defending champions.
Two teams failed to be re-elected: Bray Unknowns and Brideville, resulting in a reduction in size from ten to eight.
No new teams were elected in their place.
| Team | Location | Stadium | |
|---|---|---|---|
| Bohemians | Dublin (Phibsborough) | Dalymount Park | |
| Cork United | Cork | Mardyke | |
| Drumcondra | Dublin (Clonturk) | Clonturk Park | |
| Dundalk | Dundalk | Oriel Park | |
| Limerick | Limerick | Markets Field | |
| Shamrock Rovers | Dublin (Milltown) | Glenmalure Park | |
| Shelbourne | Dublin (Ringsend) | Shelbourne Park | |
| St. James's Gate | Dublin (Drimnagh) | Iveagh Grounds |
Shelbourne won their fourth title.