| Le Plessis-Brion | |
| Commune Status: | Commune |
| Arrondissement: | Compiègne |
| Canton: | Thourotte |
| Insee: | 60501 |
| Postal Code: | 60150 |
| Mayor: | Jean-Pierre Damien<[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Deux Vallées |
| Coordinates: | 49.4658°N 2.8911°W |
| Elevation Min M: | 33 |
| Elevation Max M: | 59 |
| Area Km2: | 7.47 |
Le Plessis-Brion (in French pronounced as /lə plɛsi bʁijɔ̃/) is a commune in the Oise department in northern France.