| Le Mesnil-Simon | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Le Mesnil-Simon (Eure-et-Loir).svg |
| Arrondissement: | Dreux |
| Canton: | Anet |
| Insee: | 28247 |
| Postal Code: | 28260 |
| Mayor: | Didier Simo[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | CA Pays de Dreux |
| Coordinates: | 48.8964°N 1.5378°W |
| Elevation M: | 130 |
| Elevation Min M: | 108 |
| Elevation Max M: | 167 |
| Area Km2: | 9.17 |
Le Mesnil-Simon (in French pronounced as /lə mɛnil simɔ̃/) is a commune in the Eure-et-Loir department in northern France.