Latarcin Explained
| Symbol: | Latarcin |
| Latarcin |
| Pfam: | PF10279 |
| Interpro: | IPR018802 |
| Opm Family: | 259 |
| Opm Protein: | 2pco |
Latarcins are short antimicrobial peptides from the venom of the spider Lachesana tarabaevi.[1] Latarcins adopt an amphipathic alpha-helical structure in the plasma membrane. Possible pharmacological applications for latarcins include antimicrobial and anticancer treatments.[2]
Notes and References
- Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV . Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity . J. Biol. Chem. . 281 . 30 . 20983–92 . July 2006 . 16735513 . 10.1074/jbc.M602168200 . free .
- Latarcins: versatile spider venom peptides. Dubovskii, P.V. . Vassilevski, A.A. . Kozlov, S.A. . Feofanov, A.V. . Grishin, E.V. . Efremov, R.G. . Cellular and Molecular Life Sciences. 2015. 72. 23. 4501–4522. 26286896. 10.1007/s00018-015-2016-x. 14177431 . 11113828.
