Lambdapapillomavirus Explained

Lambdapapillomavirus is a genus of viruses in the family Papillomaviridae.[1] Cats and dogs serve as natural hosts. There are five species in this genus. Diseases associated with this genus include mucosal and cutaneous lesions.[2] [3]

Taxonomy

The following five species are assigned to the genus:

Structure

Viruses in Lambdapapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 8kb in length.

Genus Structure Symmetry !Capsid Genomic arrangement Genomic segmentation
LambdapapillomavirusIcosahedralT=7Non-envelopedCircularMonopartite

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown.Cats and dogs serve as the natural host. Transmission routes are contact.

External links

Notes and References

  1. Van Doorslaer . K . Chen . Z . Bernard . HU . Chan . PKS . DeSalle . R . Dillner . J . Forslund . O . Haga . T . McBride . AA . Villa . LL . Burk . RD . ICTV Report Consortium . ICTV Virus Taxonomy Profile: Papillomaviridae. . The Journal of General Virology . August 2018 . 99 . 8 . 989–990 . 10.1099/jgv.0.001105 . 29927370. 6171710 .
  2. Web site: Viral Zone. ExPASy. 15 June 2015.
  3. Web site: Virus Taxonomy: 2020 Release . International Committee on Taxonomy of Viruses (ICTV) . March 2021 . 10 May 2021.