| Lake Jessie | |
| Location: | Griggs County, North Dakota |
| Coordinates: | 47.5508°N -98.2882°W |
| Type: | Lake |
| Pushpin Map: | North Dakota |
| Pushpin Map Alt: | Location of lake in North Dakota. |
Lake Jessie is a body of water located two miles east of Binford in Griggs County, in the U.S. state of North Dakota. The lake has a surface area of . It is bordered by the Lake Jessie State Historic Site. John C. Frémont named Lake Jessie for his future wife, Jessie Benton Frémont.