| Lake City High School | |
| Slogan: | "Educating Students Who Are Equipped With The Tools Necessary To Achieve success" |
| Established: | 1970 |
| Type: | Public school |
| Grades: | 9–12 |
| Principal: | Ned Blake |
| Team Name: | Panthers |
| Enrollment: | 932 (2015-16)[1] |
| Streetaddress: | 652 N. Matthews Road |
| City: | Lake City |
| State: | South Carolina |
| Country: | USA |
| Zipcode: | 29560 |
| Coordinates: | 33.871°N -79.7484°W |
| Homepage: | http://www.lchs.florence3.k12.sc.us/ |
Lake City High School is a secondary education institution located near Lake City, South Carolina. The school enrolls approximately 1,000 students.