Lacto-usp RNA motif explained

Lacto-usp RNA
Symbol:Lacto-usp RNA
Rfam:RF01710
Rna Type:sRNA
Tax Domain:Lactic acid bacteria

The Lacto-usp RNA motif is a conserved RNA structure identified in bacteria by bioinformatics.[1] Lacto-usp RNAs are found exclusively in lactic acid bacteria, and exclusively in the possible 5′ untranslated regions of (5′ UTRs) operons that contain a hypothetical gene and a usp gene. The usp gene encodes the universal stress protein. It was proposed that the Lacto-usp might correspond to the 6S RNA of the relevant species, because four of five of these species lack a predicted 6S RNA, and 6S RNAs commonly occur in 5′ UTRs of usp genes. However, given that the Lacto-usp RNA motif is much shorter than the standard 6S RNA structure, the function of Lacto-usp RNAs remains unclear.

Notes and References

  1. Weinberg Z, Wang JX, Bogue J, etal . Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes . Genome Biol . 11 . 3 . R31 . March 2010 . 20230605 . 10.1186/gb-2010-11-3-r31 . 2864571 . free .