Lactis-plasmid RNA motif explained

lactis-plasmid RNA
Symbol:lactis-plasmid RNA
Rfam:RF01742
Rna Type:sRNA
Tax Domain:lactic acid bacteria

The lactis-plasmid RNA motif is a conserved RNA structure identified by bioinformatics.[1] The RNAs are restricted to lactic acid bacteria, and are especially common in Lactococcus lactis. They typically lie near to repB genes, and are almost found in plasmids. This data suggested that lactis-plasmid RNAs participate in the control of plasmid abundance.[2] However, many of the plasmids that carry lactis-plasmid RNAs also carry ctRNA-pND324 RNAs, which are involved in plasmid copy count regulation. Therefore lactis-plasmid RNAs might have a different function.

See also

Notes and References

  1. Weinberg Z, Wang JX, Bogue J, etal . Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes . Genome Biol . 11 . 3 . R31 . March 2010 . 20230605 . 2864571 . 10.1186/gb-2010-11-3-r31 . free .
  2. Kim K, Meyer RJ . Copy-number of broad host-range plasmid R1162 is regulated by a small RNA . Nucleic Acids Res. . 14 . 20 . 8027–8046 . October 1986 . 2430262 . 311832 . 10.1093/nar/14.20.8027.