Lactate permease family explained

The lactate permease (LctP) family (TC# 2.A.14) is a family of transport proteins belonging to the ion transporter (IT) superfamily.[1]

Function

Characterized members of this family possess 15-18 transmembrane segments (TMSs) and are roughly 460-565 amino acyl residues in length.

General transport reaction

Transport reactions catalyzed by functionally characterized members of the LctP family include:[2]

D- or L-lactate or glycolate (out) + H+ (out) → D- or L-lactate or glycolate (in) + H+ (in).

Further reading

Notes and References

  1. Prakash S, Cooper G, Singhi S, Saier MH . The ion transporter superfamily . Biochimica et Biophysica Acta (BBA) - Biomembranes . 1618 . 1 . 79–92 . December 2003 . 14643936 . 10.1016/j.bbamem.2003.10.010 .
  2. Web site: 2.A.14 The Lactate Permease (LctP) Family. Transporter Classification Database. 2016-03-02.