| Lac des Mille Lacs 22A1 | |
| Official Name: | Lac des Mille Lacs Indian Reserve No. 22A1 |
| Settlement Type: | Indian reserve |
| Pushpin Map: | Canada Ontario |
| Pushpin Mapsize: | 200 |
| Coordinates: | 48.8883°N -90.3714°W |
| Coordinates Footnotes: | [1] |
| Subdivision Type: | Country |
| Subdivision Type1: | Province |
| Subdivision Type2: | District |
| Subdivision Name2: | Thunder Bay |
| Subdivision Type3: | First Nation |
| Subdivision Name3: | Lac des Mille Lacs |
| Area Land Km2: | 17.32 |
| Population Footnotes: | [2] |
| Population Total: | 0 |
| Population As Of: | 2021 |
| Population Density Km2: | 0 |
Lac des Mille Lacs 22A1 is a First Nations reserve on the shores of Lac des Mille Lacs in Thunder Bay District in northwestern Ontario, Canada. It is one of two reserves for the Lac des Mille Lacs First Nation.