| La Roche-en-Brenil | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason de la ville de La Roche-en-Brenil (Côte-d'Or).svg |
| Arrondissement: | Montbard |
| Canton: | Semur-en-Auxois |
| Insee: | 21525 |
| Postal Code: | 21530 |
| Mayor: | Joël Soilly[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Saulieu |
| Coordinates: | 47.3884°N 4.1789°W |
| Elevation Min M: | 273 |
| Elevation Max M: | 573 |
| Area Km2: | 50.85 |
La Roche-en-Brenil (in French pronounced as /la ʁɔʃ ɑ̃ bʁənil/) is a commune in the Côte-d'Or department in eastern France.