| La Milesse | |
| Commune Status: | Commune |
| Arrondissement: | Le Mans |
| Canton: | Le Mans-2 |
| Insee: | 72198 |
| Postal Code: | 72650 |
| Mayor: | Claude Loriot[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Le Mans Métropole |
| Coordinates: | 48.0653°N 0.1364°W |
| Elevation Min M: | 48 |
| Elevation Max M: | 129 |
| Area Km2: | 10.41 |
| Demonym: | Milessois, Milessoise |
La Milesse (in French pronounced as /la milɛs/) is a commune in the Sarthe department in the region of Pays de la Loire in north-western France.