| La Mé Region | |
| Native Name: | Région de la Mé |
| Native Name Lang: | fr |
| Other Name: | Massan Region Région du Massan |
| Settlement Type: | Region |
| Motto: | "Nous vous accompagnons" |
| Subdivision Type: | Country |
| Subdivision Type1: | District |
| Subdivision Name1: | Lagunes |
| Established Title: | 2011 |
| Established Date: | Established |
| Seat Type: | Regional seat |
| Seat: | Adzopé |
| Government Footnotes: | [1] |
| Leader Title: | Prefect |
| Leader Name: | Sanogo Al-Hassana |
| Leader Title1: | Council President |
| Leader Name1: | Yapi Jean-Claude Sombo |
| Unit Pref: | Metric |
| Area Footnotes: | [2] |
| Area Total Km2: | 7880 |
| Population Footnotes: | [3] |
| Population Total: | 726,665 |
| Population As Of: | 2021 census |
| Population Density Km2: | auto |
| Timezone1: | GMT |
| Utc Offset1: | +0 |
La Mé Region (also known as Massan Region) is one of the 31 regions of Ivory Coast. Since its establishment in 2011, it has been one of three regions in Lagunes District. The seat of the region is Adzopé and the region's population in the 2021 census was 726,665.
La Mé is currently divided into four departments: Adzopé, Akoupé, Alépé, and Yakassé-Attobrou.
In the 2011 decree that created the region, La Mé was referred to exclusively as the region of "Massan".[4] Since its creation, the region has more commonly been referred to as "La Mé".