| La Cluse | |
| Arrondissement: | Gap |
| Canton: | Saint-Étienne-en-Dévoluy |
| Insee: | 05042 |
| Postal Code: | 05250 |
| Commune: | Dévoluy |
| Coordinates: | 44.6403°N 5.8489°W |
| Elevation M: | 1252 |
| Elevation Min M: | 1027 |
| Elevation Max M: | 2683 |
| Area Km2: | 40.15 |
| Population: | 52 |
| Population Date: | 2019 |
| Population Footnotes: | [1] |
La Cluse (Vivaro-Alpine: La Clusa) is a former commune in the Hautes-Alpes department in southeastern France. On 1 January 2013, Agnières-en-Dévoluy, La Cluse, Saint-Disdier, and Saint-Étienne-en-Dévoluy amalgamated into the new commune of Dévoluy.