| La Última Misión | |
| Type: | studio |
| Artist: | Wisin & Yandel |
| Cover: | Wisin & Yandel - La Última Misión.jpg |
| Border: | yes |
| Released: | |
| Length: | 1:21:01 |
| Language: | Spanish |
| Label: | Sony Latin |
| Prev Title: | Los Campeones del Pueblo |
| Prev Year: | 2022 |
La Última Misión (English: The Last Mission) is the tenth and final studio album by Puerto Rican music duo Wisin & Yandel. It was released on September 30, 2022, by Sony Music Latin. This album announced that they are breaking up.