LYPD3 explained

Ly6/PLAUR domain-containing protein 3 is a protein that in humans is encoded by the LYPD3 gene.^{[1] [2] [3]}

Further reading

• Paret C, Hildebrand D, Weitz J, etal . C4.4A as a candidate marker in the diagnosis of colorectal cancer. . Br. J. Cancer . 97 . 8 . 1146–56 . 2007 . 17912244 . 10.1038/sj.bjc.6604012 . 2360445 .
• Kimura K, Wakamatsu A, Suzuki Y, etal . Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. . Genome Res. . 16 . 1 . 55–65 . 2006 . 16344560 . 10.1101/gr.4039406 . 1356129 .
• Otsuki T, Ota T, Nishikawa T, etal . Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. . DNA Res. . 12 . 2 . 117–26 . 2007 . 16303743 . 10.1093/dnares/12.2.117 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Suzuki Y, Yamashita R, Shirota M, etal . Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. . Genome Res. . 14 . 9 . 1711–8 . 2004 . 15342556 . 10.1101/gr.2435604 . 515316 .
• Grimwood J, Gordon LA, Olsen A, etal . The DNA sequence and biology of human chromosome 19. . Nature . 428 . 6982 . 529–35 . 2004 . 15057824 . 10.1038/nature02399 . 2004Natur.428..529G . free .
• Hansen LV, Gårdsvoll H, Nielsen BS, etal . Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor. . Biochem. J. . 380 . Pt 3 . 845–57 . 2004 . 15012588 . 10.1042/BJ20031478 . 1224211 .
• Clark HF, Gurney AL, Abaya E, etal . The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. . Genome Res. . 13 . 10 . 2265–70 . 2003 . 12975309 . 10.1101/gr.1293003 . 403697 .
• Fletcher GC, Patel S, Tyson K, etal . hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan. . Br. J. Cancer . 88 . 4 . 579–85 . 2003 . 12592373 . 10.1038/sj.bjc.6600740 . 2377166 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Adam PJ, Boyd R, Tyson KL, etal . Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer. . J. Biol. Chem. . 278 . 8 . 6482–9 . 2003 . 12477722 . 10.1074/jbc.M210184200 . free .

Notes and References

1. Wurfel J, Seiter S, Stassar M, Claas A, Klas R, Rosel M, Marhaba R, Savelyeva L, Schwab M, Matzku S, Zoller M . Cloning of the human homologue of the metastasis-associated rat C4.4A . Gene . 262 . 1–2 . 35–41 . Feb 2001 . 11179665 . 10.1016/S0378-1119(00)00515-1 .
2. Smith BA, Kennedy WJ, Harnden P, Selby PJ, Trejdosiewicz LK, Southgate J . Identification of genes involved in human urothelial cell-matrix interactions: implications for the progression pathways of malignant urothelium . Cancer Res . 61 . 4 . 1678–85 . Mar 2001 . 11245483 .
3. Web site: Entrez Gene: LYPD3 LY6/PLAUR domain containing 3.