Latent TGF-beta binding protein explained
The latent TGF-beta binding proteins (LTBP) are a family of carrier proteins.
LTBP is a family of secreted multidomain proteins that were originally identified by their association with the latent form of transforming growth factors. They interact with a variety of extracellular matrix proteins and may play a role in the regulation of TGF beta bioavailability.
Genes
latent transforming growth factor beta binding protein 4 |
Hgncid: | 6717 |
Symbol: | LTBP4 |
Altsymbols: | LTBP-4, LTBP-4L |
Entrezgene: | 8425 |
Omim: | 604710 |
Refseq: | NM_003573 |
Uniprot: | Q8N2S1 |
Chromosome: | 19 |
Arm: | q |
Band: | 13.1 |
Locussupplementarydata: | -13.2 |
External links
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Latent-transforming growth factor beta-binding protein 1