Latent TGF-beta binding protein explained

The latent TGF-beta binding proteins (LTBP) are a family of carrier proteins.

LTBP is a family of secreted multidomain proteins that were originally identified by their association with the latent form of transforming growth factors. They interact with a variety of extracellular matrix proteins and may play a role in the regulation of TGF beta bioavailability.

Genes

latent transforming growth factor beta binding protein 1
Hgncid:6714
Symbol:LTBP1
Altsymbols:TGF-beta1-BP-1
Entrezgene:4052
Omim:150390
Refseq:NM_206943
Uniprot:Q14766
Chromosome:2
Arm:p
Band:22
Locussupplementarydata:-p21
latent transforming growth factor beta binding protein 2
Hgncid:6715
Symbol:LTBP2
Altsymbols:LTBP3, C14orf141
Entrezgene:4053
Omim:602091
Refseq:NM_000428
Uniprot:Q14767
Chromosome:14
Arm:q
Band:24.3
latent transforming growth factor beta binding protein 3
Hgncid:6716
Symbol:LTBP3
Altsymbols:LTBP2
Entrezgene:4054
Omim:602090
Refseq:NM_021070
Uniprot:Q9NS15
Chromosome:11
Arm:q
Band:12
latent transforming growth factor beta binding protein 4
Hgncid:6717
Symbol:LTBP4
Altsymbols:LTBP-4, LTBP-4L
Entrezgene:8425
Omim:604710
Refseq:NM_003573
Uniprot:Q8N2S1
Chromosome:19
Arm:q
Band:13.1
Locussupplementarydata:-13.2

External links