LMLN explained
Leishmanolysin-like (metallopeptidase M8 family) is a protein that in humans is encoded by the LMLN gene.[1]
Function
This gene encodes a zinc-metallopeptidase. The encoded protein may play a role in cell migration and invasion. Studies of a similar protein in Drosophila indicate a potential role in mitotic progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009].
Further reading
- Cobbe N, Marshall KM, Gururaja Rao S, Chang CW, Di Cara F, Duca E, Vass S, Kassan A, Heck MM . The conserved metalloprotease invadolysin localizes to the surface of lipid droplets . Journal of Cell Science . 122 . Pt 18 . 3414–23 . September 2009 . 19706689 . 2736869 . 10.1242/jcs.044610 .
- McHugh B, Krause SA, Yu B, Deans AM, Heasman S, McLaughlin P, Heck MM . Invadolysin: a novel, conserved metalloprotease links mitotic structural rearrangements with cell migration . The Journal of Cell Biology . 167 . 4 . 673–86 . November 2004 . 15557119 . 2172566 . 10.1083/jcb.200405155 .
Notes and References
- Web site: Entrez Gene: Leishmanolysin-like (metallopeptidase M8 family) .