LGI2 explained

Leucine-rich repeat LGI family member 2 is a protein that in humans is encoded by the LGI2 gene.^{[1] [2] [3]}

Further reading

• Staub E, Pérez-Tur J, Siebert R, etal . The novel EPTP repeat defines a superfamily of proteins implicated in epileptic disorders . Trends Biochem. Sci. . 27 . 9 . 441–4 . 2002 . 12217514 . 10.1016/S0968-0004(02)02163-1 .
• Andersson B, Wentland MA, Ricafrente JY, etal . A "double adaptor" method for improved shotgun library construction . Anal. Biochem. . 236 . 1 . 107–13 . 1996 . 8619474 . 10.1006/abio.1996.0138 .
• Yu W, Andersson B, Worley KC, etal . Large-Scale Concatenation cDNA Sequencing . Genome Res. . 7 . 4 . 353–8 . 1997 . 9110174 . 10.1101/gr.7.4.353. 139146 .
• Nagase T, Kikuno R, Ohara O . Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins . DNA Res. . 8 . 4 . 179–87 . 2002 . 11572484 . 10.1093/dnares/8.4.179 . free .
• Scheel H, Tomiuk S, Hofmann K . A common protein interaction domain links two recently identified epilepsy genes . Hum. Mol. Genet. . 11 . 15 . 1757–62 . 2003 . 12095917 . 10.1093/hmg/11.15.1757 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Wang L, Zhu YF, Guo XJ, etal . A two-dimensional electrophoresis reference map of human ovary . J. Mol. Med. . 83 . 10 . 812–21 . 2006 . 16021519 . 10.1007/s00109-005-0676-y . 6644433 .

Notes and References

1. Gu W, Wevers A, Schroder H, Grzeschik KH, Derst C, Brodtkorb E, de Vos R, Steinlein OK . The LGI1 gene involved in lateral temporal lobe epilepsy belongs to a new subfamily of leucine-rich repeat proteins . FEBS Lett . 519 . 1–3 . 71–6 . May 2002 . 12023020 . 10.1016/S0014-5793(02)02713-8 . 41639083 . free .
2. Gu W, Gibert Y, Wirth T, Elischer A, Bloch W, Meyer A, Steinlein OK, Begemann G . Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders . Mol Biol Evol . 22 . 11 . 2209–16 . Oct 2005 . 16014869 . 10.1093/molbev/msi214 . free . 10536/DRO/DU:30063551 . free .
3. Web site: Entrez Gene: LGI2 leucine-rich repeat LGI family, member 2.