LGD-2941 explained

Cas Number:847235-85-2
Pubchem:16750192
Drugbank:05234
Chemspiderid:24694857
Unii:27H8PR7JGK
Chembl:467888
Iupac Name:6-[(2R,5R)-2-methyl-5-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-4-(trifluoromethyl)-1H-quinolin-2-one
C:17
H:16
F:6
N:2
O:2
Stdinchi:InChI=1S/C17H16F6N2O2/c1-8-2-5-13(15(27)17(21,22)23)25(8)9-3-4-12-10(6-9)11(16(18,19)20)7-14(26)24-12/h3-4,6-8,13,15,27H,2,5H2,1H3,(H,24,26)/t8-,13-,15-/m1/s1
Stdinchikey:HWLLYFXDDGGHOE-BCSUUIJWSA-N
Smiles:C[C@@H]1CC[C@@H](N1C2=CC3=C(C=C2)NC(=O)C=C3C(F)(F)F)[C@H](C(F)(F)F)O

LGD-2941 is a drug which acts as a selective androgen receptor modulator (SARM).[1] It is no longer being developed.[2]

Notes and References

  1. Long YO, Higuchi RI, Caferro TR, Lau TL, Wu M, Cummings ML, Martinborough EA, Marschke KB, Chang WY, López FJ, Karanewsky DS, Zhi L . Selective androgen receptor modulators based on a series of 7H-[1,4]oxazino[3,2-g]quinolin-7-ones with improved in vivo activity . Bioorganic & Medicinal Chemistry Letters . 18 . 9 . 2967–71 . May 2008 . 18400499 . 10.1016/j.bmcl.2008.03.062 .
  2. Web site: LGD 2941 . AdisInsight . Springer Nature Switzerland AG .