L-threo-3-Methylaspartate explained

-threo-3-Methylaspartate is an unusual amino acid formed by glutamate mutase and can be metabolised by methylaspartate ammonia-lyase. It is found in the structures of the antibiotics friulimicin^[1] and vicenistatin^[1] and in carbon metabolism of haloarchaea (Methylaspartate cycle).^[2]

Notes and References

1. 10.1038/ja.2005.62. 16161486. Involvement of Glutamate Mutase in the Biosynthesis of the Unique Starter Unit of the Macrolactam Polyketide Antibiotic Vicenistatin. The Journal of Antibiotics. 58. 7. 468–72. 2005. Ogasawara . Y. . Kakinuma . K. . Eguchi . T. . free.
2. 10.1126/science.1196544. 21252347. A Methylaspartate Cycle in Haloarchaea. Science. 331. 6015. 334–7. 2011. Khomyakova . M.. Bukmez . O.. Thomas . L. K.. Erb . T. J.. Berg . I. A.. 2011Sci...331..334K. 206529403.