L-Sorbose 1-dehydrogenase explained

L-sorbose 1-dehydrogenase
Ec Number:	1.1.99.32

-Sorbose 1-dehydrogenase (SDH) is an enzyme with systematic name -sorbose:acceptor 1-oxidoreductase.^[1] This enzyme catalyses the following chemical reaction

-sorbose + acceptor

\rightleftharpoons 1-dehydro-L-sorbose + reduced acceptor

The product, -sorbosone, is an intermediate in bacterial 2-keto-L-gulonic-acid formation. Co²⁺ stimulate activity of this membrane-bound enzyme, while Cu²⁺ act as an inhibitor.

Notes and References

1. Isolation and characterization of membrane-bound -sorbose dehydrogenase from Gluconobacter melanogenus UV10 . Sugisawa T, Hoshino T, Nomura S, Fujiwara A . Agric. Biol. Chem. . 1991 . 55 . 363–370 . 10.1271/bbb1961.55.363. free .