L-rhamnose 1-dehydrogenase explained

L-rhamnose 1-dehydrogenase
Ec Number:	1.1.1.173
Cas Number:	52227-67-5
Go Code:	0050034

In enzymology, a L-rhamnose 1-dehydrogenase is an enzyme that catalyzes the chemical reaction

L-rhamnofuranose + NAD⁺

\rightleftharpoons L-rhamno-1,4-lactone + NADH + H⁺

Thus, the two substrates of this enzyme are L-rhamnofuranose and NAD⁺, whereas its 3 products are L-rhamno-1,4-lactone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is L-rhamnofuranose:NAD⁺ 1-oxidoreductase. This enzyme participates in fructose and mannose metabolism.

References

• 10.1139/m85-153 . Rigo LU, Marechal LR, Vieira MM, Veiga LA . 1985 . Oxidative pathway for L-rhamnose degradation in Pullularia pullulans . Can. J. Microbiol. . 31 . 9 . 817 - 822 .
• Rigo LU, Nakano M, Veiga LA, Feingold DS . 1976 . L-Rhamnose dehydrogenase of Pullularia pullulans . Biochim. Biophys. Acta . 445 . 286 - 93 . 8142 . 2 . 10.1016/0005-2744(76)90083-8.