L-myc internal ribosome entry site (IRES) | |
Symbol: | IRES_L-myc |
Rfam: | RF00261 |
Rna Type: | Cis-reg |
Tax Domain: | Eukaryota |
The L-myc internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of L-myc that allows cap-independent translation. L-myc undergoes translation via the internal ribosome entry site and bypasses the typical eukaryotic cap-dependent translation pathway [1]. The myc family of genes when expressed are known to be involved in the control of cell growth, differentiation and apoptosis.