L-myc internal ribosome entry site (IRES) explained

L-myc internal ribosome entry site (IRES)
Symbol:IRES_L-myc
Rfam:RF00261
Rna Type:Cis-reg
IRES
Tax Domain:Eukaryota

The L-myc internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of L-myc that allows cap-independent translation. L-myc undergoes translation via the internal ribosome entry site and bypasses the typical eukaryotic cap-dependent translation pathway [1]. The myc family of genes when expressed are known to be involved in the control of cell growth, differentiation and apoptosis.

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