| L-gulonate 3-dehydrogenase | |
| Ec Number: | 1.1.1.45 |
| Cas Number: | 9028-51-7 |
| Go Code: | 0050104 |
| Width: | 270 |
In enzymology, a L-gulonate 3-dehydrogenase is an enzyme that catalyzes the chemical reaction
L-gulonate + NAD+
\rightleftharpoons
Thus, the two substrates of this enzyme are L-gulonate and NAD+, whereas its 3 products are 3-dehydro-L-gulonate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-gulonate:NAD+ 3-oxidoreductase. Other names in common use include L-3-aldonate dehydrogenase, L-3-aldonic dehydrogenase, L-gulonic acid dehydrogenase, L-beta-hydroxyacid dehydrogenase, L-beta-hydroxy-acid-NAD+-oxidoreductase, and L-3-hydroxyacid dehydrogenase. This enzyme participates in pentose and glucuronate interconversions.
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .