| L-amino-acid alpha-ligase | |
| Ec Number: | 6.3.2.28 |
In enzymology, an L-amino-acid alpha-ligase is an enzyme that catalyzes the chemical reaction
ATP + an L-amino acid + an L-amino acid
\rightleftharpoons
Thus, the two substrates of this enzyme are ATP and L-amino acid, whereas its 3 products are ADP, phosphate, and L-aminoacyl-L-amino acid.
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases). The systematic name of this enzyme class is L-amino acid:L-amino acid ligase (ADP-forming). Other names in common use include L-amino acid alpha-ligase, bacilysin synthetase, YwfE, and L-amino acid ligase.