L-687,384 Explained
L-687,384 is a sigma receptor agonist, selective for the σ1 subtype,[1] as well as an NMDA antagonist.[2]
References
- Bergeron R, Debonnel G . Effects of low and high doses of selective sigma ligands: further evidence suggesting the existence of different subtypes of sigma receptors . Psychopharmacology . 129 . 3 . 215–24 . February 1997 . 9084059 . 10.1007/s002130050183. 24537111 .
- McLarnon J, Sawyer D, Church J . The actions of L-687,384, a sigma receptor ligand, on NMDA-induced currents in cultured rat hippocampal pyramidal neurons . Neuroscience Letters . 174 . 2 . 181–4 . June 1994 . 7526288 . 10.1016/0304-3940(94)90016-7. 10876486 .