L-3-cyanoalanine synthase explained
| L-3-cyanoalanine synthase |
| Ec Number: | 4.4.1.9 |
| Cas Number: | 9059-53-4 |
| Go Code: | 0050017 |
The enzyme L-3-cyanoalanine synthase (EC 4.4.1.9) catalyzes the chemical reaction
L-cysteine + hydrogen cyanide
L-3-cyanoalanine +
hydrogen sulfideThis enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide L-3-cyanoalanine-forming). Other names in common use include β-cyanoalanine synthase, β-cyanoalanine synthetase, β-cyano-L-alanine synthase, and L-cysteine hydrogen-sulfide-lyase (adding HCN). This enzyme participates in cyanoamino acid metabolism.
References
- Akopyan TN, Braunstein AE, Goryachenkova EV . 1975 . β-Cyanoalanine synthase: purification and characterization . Proc. Natl. Acad. Sci. U.S.A. . 72 . 1617 - 21 . 1055433 . 10.1073/pnas.72.4.1617 . 4 . 432590 . 1975PNAS...72.1617A . free .
- Castric PA, Conn EE . Eric Conn (biochemist) . 1971 . Formation of β-cyanoalanine by O-acetylserine sulfhydrylase . J. Bacteriol. . 108 . 132 - 6 . 5001194 . 1 . 10.1128/jb.108.1.132-136.1971 . 247041 .
- Hendrickson HR . 1968 . The β-cyanoalanine synthase of blue lupine . Fed. Proc. . 27 . 593 .
- Hendrickson HR, Conn EE . 1969 . Cyanide metabolism in higher plants. IV. Purification and properties of the β-cyanolanine synthase of blue lupine . J. Biol. Chem. . 244 . 2632 - 40 . 5769995 . 10 . 10.1016/S0021-9258(18)83446-9 . free .
