L-2-amino-4-chloropent-4-enoate dehydrochlorinase explained

L-2-amino-4-chloropent-4-enoate dehydrochlorinase
Ec Number:	4.5.1.4
Cas Number:	113066-37-8
Go Code:	0047460

The enzyme L-2-amino-4-chloropent-4-enoate dehydrochlorinase (EC 4.5.1.4) catalyzes the reaction

L-2-amino-4-chloropent-4-enoate + H₂O

\rightleftharpoons 2-oxopent-4-enoate + chloride + NH₃

This enzyme belongs to the family of lyases, specifically the class of carbon-halide lyases. The systematic name of this enzyme class is L-2-amino-4-chloropent-4-enoate chloride-lyase (adding water; deaminating; 2-oxopent-4-enoate-forming). Other names in common use include L-2-amino-4-chloro-4-pentenoate dehalogenase, and L-2-amino-4-chloropent-4-enoate chloride-lyase (deaminating).

References

• Moriguchi M, Hoshino S, ((Hatanaka S-I)) . 1987 . Dehalogenation and deamination of l-2-amino-4-chloro-4-pentenoic acid by Proteus mirabilis . Agric. Biol. Chem. . 51 . 12 . 3295–3299 . 10.1271/bbb1961.51.3295. free .