| Lê Minh Khái | |
| Office: | Deputy Prime Minister of Vietnam |
| Predecessor: | Vương Đình Huệ |
| Termstart: | 8 April 2021 |
| Office1: | Inspector-General of the Government |
| Predecessor1: | Phan Văn Sáu |
| Successor1: | Đoàn Hồng Phong |
| Termstart1: | 26 October 2017 |
| Termend1: | 7 April 2021 |
| Birth Date: | 10 December 1964 |
| Birth Place: | Phước Long district, Bạc Liêu province, South Vietnam |
| Occupation: | Politician |
| Nationality: | Vietnam |
| Party: | Communist Party of Vietnam (1990–present) |
| Website: | https://leminhkhai.chinhphu.vn |
| Primeminister: | Phạm Minh Chính |
| Primeminister1: | Nguyễn Xuân Phúc Phạm Minh Chính |
| Caption: | Lê Minh Khái in 2020 |
Lê Minh Khái (born 10 December 1964) is a politician of the Communist Party of Vietnam. He is Deputy Prime Minister for General Economics in the Government of Vietnam.[1]