| L'Isle-Arné | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr L'Isle-Arné (Gers).svg |
| Arrondissement: | Auch |
| Canton: | Auch-2 |
| Insee: | 32157 |
| Postal Code: | 32270 |
| Mayor: | Sébastien Ghion[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 43.6164°N 0.7719°W |
| Elevation M: | 155 |
| Elevation Min M: | 149 |
| Elevation Max M: | 234 |
| Area Km2: | 6.97 |
L'Isle-Arné (in French pronounced as /lil aʁne/; Occitan (post 1500);: La Ileta e Arnès) is a commune in the Gers department in southwestern France.