| Settlement Type: | Town |
| Official Name: | Kyainseikgyi |
| Pushpin Label Position: | bottom |
| Pushpin Map: | Myanmar |
| Pushpin Map Caption: | Location in Myanmar (Burma) |
| Subdivision Type: | Country |
| Subdivision Name: |  Myanmar |
| Subdivision Type1: | Division |
| Subdivision Type2: | District |
| Subdivision Name2: | Kyainn Seikkyi District |
| Subdivision Type3: | Township |
| Subdivision Name3: | Kyain Seikgyi Township |
| Unit Pref: | Imperial |
| Area Code: | 58[1] |
| Population: | 4,428 |
| Population As Of: | 2014 |
| Population Footnotes: | [2] |
| Population Blank1 Title: | Ethnicities |
| Population Blank2: | Buddhism and Christianity |
| Population Blank2 Title: | Religions |
| Population Density Km2: | auto |
| Coordinates: | 16.0333°N 98.1333°W |
| Leader Title: | Mayor |
| Elevation M: | 19 |
| Timezone: | MMT |
| Utc Offset: | +6.30 |
Kyainseikgyi (Phlone: ; Burmese: ကြာအင်းဆိပ်ကြီးမြို့; in Burmese pronounced as /tɕàʔɪ́ɰ̃sʰeɪ̯ʔtɕí mjo̰/) is a town in Kayin State, Myanmar, located on the eastern side of the Zami River. It is the administrative center of the Kyain Seikgyi Township.