| Honorific-Prefix: | The Honourable |
| Kwamena Duncan | |
| Office: | Regional Minister |
| Term Start: | February 2017 |
| President: | Nana Akuffo-Addo |
| Successor: | Incumbent |
| Birth Place: | Ghana |
| Nationality: | Ghanaian |
| Party: | New Patriotic Party |
| Alma Mater: | Mfantsipim School |
| Profession: | Educationist |
Kwamena Duncan is a Ghanaian educationist and politician. He is a member of the New Patriotic Party in Ghana. He is the Central Regional minister of Ghana.[1] He was appointed by President Nana Addo Danquah Akuffo-Addo in January 2017 and was approved by the Members of Parliament in February 2017.[2] He is also former Central Regional Secretary of the New Patriotic Party