Kurzrock–Miller test explained

The Kurzrock–Miller test is an in-vitro test of sperm–mucus interaction. It consists of establishing an interface between cervical mucus and liquefied semen.^[1] It is one of the tests used for investigating infertility.

Etymology

The test is named after Raphael Kurzrock and Thomas Grier Miller.^[2]

Interpretation

1. Negative test: Spermatozoa congregate on semen side of the interface, but do not penetrate it.
2. Abnormal: Spermatozoa penetrate the mucus, but rapidly become immobile or acquire shaking movement.
3. Poor: after penetration, spermatozoa do not progress farther than 500 μm.
4. Normal: Spermatozoa penetrate the mucus and >90% are motile with definite progression, crossing 3 cm at 30 minutes.^[3]

See also

• Hamster egg penetration test
• Postcoital test
• Sperm–cervical mucus contact test

Notes and References

1. Book: Mortimer, David. Practical laboratory andrology. 1994. Oxford University Press. New York. 9780195065954. 186–188.
2. Web site: Kurzrock-Miller test. Whonamedit?. 3 July 2013.
3. Padubidri; Daftary (2011). Shaw's Textbook of Gynaecology, 15e. p. 204.