| Official Name: | Krathum Baen |
| Native Name: | กระทุ่มแบน |
| Native Name Lang: | th |
| Settlement Type: | District |
| Subdivision Type: | Country |
| Subdivision Name: | Thailand |
| Subdivision Type1: | Province |
| Subdivision Name1: | Samut Sakhon |
| Subdivision Type2: | Seat |
| Subdivision Type3: | Subdistrict |
| Subdivision Type4: | Muban |
| Established Title: | District established |
| Population Total: | 17 |
| Population As Of: | 2017 |
| Blank Name Sec1: | Postal code |
| Blank Info Sec1: | 74110, 74130 |
| Blank Name Sec2: | Geocode |
| Blank Info Sec2: | 7402 |
| Timezone: | ICT |
| Utc Offset: | +7 |
| Coordinates: | 13.6558°N 100.2678°W |
Krathum Baen (in Thai pronounced as /krā.tʰûm bɛ̄ːn/) is a district (amphoe) in the northern part of Samut Sakhon province, central Thailand.
Krathum Baen was a part of Mueang Samut Sakhon district. It was created in 1900. In 1926 the government added Tambons Tha Mai, Bang Yang, Nong Kok Khai, and Om Noi of Sam Phran district, Nakhon Pathom province to the district.
Neighbouring districts are (from the north clockwise): Sam Phran of Nakhon Pathom province; Nong Khaem and Bang Bon of Bangkok; Mueang Samut Sakhon and Ban Phaeo of Samut Sakhon Province.
The important water resources are the Tha Chin river and Phasi Charoen canal.
The name Krathum Baen meaning 'flat burflower-tree'.
The district is divided into 10 subdistricts (tambons), which are further subdivided into 76 villages (mubans). There is a city (thesaban nakhon), Om Noi, and a town (thesaban mueang), Krathum Baen. The non-municipal area is administered by eight tambon administrative organizations (TAO).
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Krathum Baen Hospital is a general hospital operated by the Ministry of Public Health.