| Kpana Lewis | |
| Birth Date: | April 18, 1830 |
| Birth Place: | Sherbro Island, British Sierra Leone |
| Death Place: | Accra, Gold Coast |
| Nationality: | Sierra Leonean |
| Residence: | Sherbro Island, Sierra Leone |
| Occupation: | Sherbro chief and an opponent of colonial rule of the British in Sierra Leone. |
| Profession: | Warrior, tribal leader |
Kpana Lewis (April 19, 1830 – May 10, 1912) was a Sherbro chief from Sierra Leone and an opponent of colonial rule of the British. He exercised strong influence over all Sherbro chiefs.
Kpana Lewis was born in 1830 in Sherbro Island in the Southern Province of British Sierra Leone to a politically dominant family of the Sherbro aristocracy. His grandfather, Bai Kong Kuba Lewis was the most dominant king among all of the Sherbro people.