| Honorific-Prefix: | Honourable |
| Kombo Khamis Kombo | |
| Honorific-Suffix: | MP |
| Office: | Member of Parliament for Mgogoni |
| Term Start: | November 2010 |
| Predecessor: | Mohamed Ali Said |
| Birth Date: | 15 February 1963 |
| Birth Place: | Sultanate of Zanzibar |
| Nationality: | Tanzanian |
| Party: | CUF |
Kombo Khamis Kombo (born 15 February 1963) is a Tanzanian CUF politician and Member of Parliament for Mgogoni constituency since 2010.[1]