| Official Name: | Knowlesville, New York |
| Pushpin Map: | New York#USA |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | New York |
| Subdivision Type2: | County |
| Subdivision Name2: | Orleans |
| Timezone: | Eastern (EST) |
| Utc Offset: | -5 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | -4 |
| Elevation Ft: | 512 |
| Coordinates: | 43.2419°N -78.3106°W |
| Postal Code Type: | ZIP code |
| Postal Code: | 14479 |
| Area Code: | 585 |
| Blank Name: | GNIS feature ID |
| Blank Info: | 954790 |
Knowlesville is a hamlet in Orleans County, New York, United States. The community is located along the Erie Canal, east-northeast of Medina. Knowlesville had a post office from March 11, 1826, until July 4, 2009; it still has its own ZIP code, 14479.[1] [2]