| Official Name: | Klisura |
| Native Name: | Клисура |
| Settlement Type: | Village |
| Pushpin Map: | Bulgaria |
| Pushpin Label Position: | Location in Bulgaria |
| Subdivision Name: |  Bulgaria |
| Subdivision Type1: | Province |
| Subdivision Name1: | Blagoevgrad Province |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Blagoevgrad |
| Leader Title: | Suffragan Mayor |
| Leader Name: | Kiril Ivanovski |
| Area Total Km2: | 19.136 |
| Population As Of: | 15 December 2010[1] |
| Population Note: | GRAO |
| Population Total: | 27 |
| Timezone: | EET |
| Utc Offset: | +2 |
| Timezone Dst: | EEST |
| Utc Offset Dst: | +3 |
| Postal Code Type: | Postal Code |
| Postal Code: | 2738 |
| Area Code: | 07413 |
| Coordinates: | 42.0167°N 77°W |
| Elevation M: | 990 |
Klisura is a sparsely populated and dispersed, composed of several almost abandoned neighborhoods village in Blagoevgrad Municipality, in Blagoevgrad Province, Bulgaria. It is situated in the Vlahina mountain, bordering with North Macedonia to the west and Kyustendil Province to the north. The area is covered with oak and beech forests. There are remains of prehistorical village nearby.