Klaus Lauer Explained

Klaus Lauer (born 1950) is a German neuroepidemologist, mostly known for his work on multiple sclerosis (MS).

Early life

Klaus Joachim Lauer was born in 1950 and studied medicine in Frankfurt (Germany) from 1968 to 1975. He became a resident in the Department of Neurology of Klinikum Darmstadt, the Academic Teaching Hospital of Frankfurt University (Akademisches Lehrkrankenhaus der Universitäten Frankfurt/Main und Heidelberg-Mannheim, a major healthcare institution in South Hesse. Besides clinical work, Lauer devoted most of his research to epidemiology, with a special focus on MS etiology.

Career

Early on, he published a series of five articles[1] [2] [3] [4] [5] on multiple sclerosis in the land of Hesse with Wolfgang Firnhaber, who had already been studying MS epidemiology in Göttingen and Darmstadt,[6] with support from the Hertie Foundation, the German Research Foundation and the Stifterverband für die Deutsche Wissenschaft. His lasting collaboration with Prof. Firnhaber, a longtime expert in MS prognostication[7] [8] [9] and geomedical aspects of MS,[10] provided K. Lauer with a solid background in geomedical investigation.[11] [12]

In the mid 80's, Lauer launched a series of specialized reports in Scandinavia, starting with a study of multiple sclerosis in Western Norway published in Neurology.[13] He has been following Norvegian MS ever since [14] [15] and has also coauthored epidemiological studies in Sweden with Anne-Marie Landtblom and Inger Boström.[16]

Like John Kurtzke,[17] Klaus J. Lauer has dedicated a large part of his work to the study of MS in the Faroe Islands,[18] starting with a 1986 article in the Journal of Neurology entitled "Some comments on the occurrence of multiple sclerosis in the Faroe Islands",[19] followed in 1988 by "Multiple sclerosis in relation to industrial and commercial activities in the Faroe Islands"[20] in the journal Neuroepidemiology, followed one year later by "Dietary changes in temporal relation to multiple sclerosis in the Faroe Islands: an evaluation of literary sources"[21] in the same journal.

MS is generally considered a multifactorial disease,[22] in which genetic predispositions and environmental triggers combine to launch an autoimmune process. As an international expert on the environmental dimension of MS,[23] Lauer compiled a review in Expert Review of Neurotherapeutics.[24]

Since 1992, Lauer has published a large number of epidemiological studies covering most west European countries,[25] [26] [27] [28] [29] Russia,[30] the USA,[31] [32] Canada, some countries in Asia and the Middle-East,[33] with a special focus on dietary aspects of etiology.[34] [35] [36] [37] Most recently, Klaus Lauer has focused again on MS in the Faroes [38] [39] and has been involved as an expert in the steering committee of the EnviMS study, a major multi-countries study investigating the impact of environmental exposures on MS.[40] [41] [42] Lauer is also one of the authors of a reference study of the cost of MS in Europe[43] and of several publications dealing with technical and methodological considerations in neuroepidemiology applied to multiple sclerosis.[44] [45]

External links

Notes and References

  1. Lauer K, Firnhaber W, Reining R, Leuchtweis B . Epidemiological investigations into multiple sclerosis in southern Hesse. I. Methodological problems and basic epidemiologic characteristics . Acta Neurologica Scandinavica . 70 . 4 . 257–65 . October 1984 . 6507035 . 10.1111/j.1600-0404.1984.tb00823.x. 37474492 .
  2. Lauer K, Firnhaber W . Epidemiological investigations into multiple sclerosis in southern Hesse. II. The distribution of cases in relation to exogenous features . Acta Neurologica Scandinavica . 70 . 4 . 266–73 . October 1984 . 6507036 . 10.1111/j.1600-0404.1984.tb00824.x. 11874178 . free .
  3. Lauer K, Firnhaber W . Epidemiological investigations into multiple sclerosis in Southern Hesse. III. The possible influence of occupation on the risk of disease . Acta Neurologica Scandinavica . 72 . 4 . 397–402 . October 1985 . 4082904 . 10.1111/j.1600-0404.1985.tb00890.x. 28427761 . free .
  4. Lauer K, Firnhaber W . Epidemiological investigations into multiple sclerosis in Southern Hesse. IV. The influence of urban and rural environment on disease risk . Acta Neurologica Scandinavica . 72 . 4 . 403–6 . October 1985 . 4082905 . 10.1111/j.1600-0404.1985.tb00891.x. 36477076 . free .
  5. Lauer K, Firnhaber W . Epidemiological investigations into multiple sclerosis in Southern Hesse. V. Course and prognosis . Acta Neurologica Scandinavica . 76 . 1 . 12–7 . July 1987 . 3498287 . 10.1111/j.1600-0404.1987.tb03537.x. 32088559 . free .
  6. Web site: Deutsches Ärzteblatt international: Multiple Sclerosis Registry in Germany – Results of the Extension Phase 2005/2006: Article of 30 Years Ago (25.04.2008) . Aerzteblatt.de . 2008-04-25 . 2015-04-01.
  7. Bauer HJ, Firnhaber W, Winkler W . Prognostic criteria in multiple sclerosis . Annals of the New York Academy of Sciences . 122 . 1. 542–51 . March 1965 . 14313511 . 10.1111/j.1749-6632.1965.tb20234.x. 1965NYASA.122..542B . 31948757 .
  8. Bauer H, Firnhaber W . Zur Leistungsprognose Multiple-Sklerose-Kranker . On the prognosis of work capacity in patients with multiple sclerosis . de . Deutsche Medizinische Wochenschrift . 88 . 27. 1357–64 . July 1963 . 13966928 . 10.1055/s-0028-1112108.
  9. Lauer K, Firnhaber W . Prognostic criteria in an epidemiological group of patients with multiple sclerosis: an exploratory study . Journal of Neurology . 239 . 2 . 93–7 . February 1992 . 1552310 . 10.1007/BF00862981. 24945652 .
  10. Firnhaber W . [Multiple sclerosis. Methods and results of a geomedical study] . de . Fortschritte der Medizin . 90 . 14 . 551–4 . May 1972 . 5072275.
  11. Poser S, Poser W, Schlaf G, etal . Prognostic indicators in multiple sclerosis . Acta Neurologica Scandinavica . 74 . 5 . 387–92 . November 1986 . 3825497 . 10.1111/j.1600-0404.1986.tb03531.x. 42211498 .
  12. Prange AJ, Lauer K, Poser S, etal . Epidemiological aspects of multiple sclerosis: a comparative study of four centres in Europe . Neuroepidemiology . 5 . 2 . 71–9 . 1986 . 3785525 . 10.1159/000110816.
  13. Lauer K, Firnhaber W . Western Norway: a high-risk area for MS . Neurology . 35 . 9 . 1392 . September 1985 . 4022391 . 10.1212/wnl.35.9.1392. 41877517 .
  14. Risberg G, Aarseth JH, Nyland H, Lauer K, Myhr KM, Midgard R . Prevalence and incidence of multiple sclerosis in Oppland County: a cross-sectional population-based study in a landlocked county of Eastern Norway . Acta Neurologica Scandinavica . 124 . 4 . 250–7 . October 2011 . 21143594 . 10.1111/j.1600-0404.2010.01465.x. 22178018 .
  15. Lauer K . Multiple sclerosis in Nordland County . Tidsskrift for den Norske Lægeforening . 126 . 5 . 637–8 . February 2006 . 16505886 .
  16. Boström I, Landtblom AM, Lauer K . An ecological study of industry in a high-risk region of multiple sclerosis . Journal of the Neurological Sciences . 311 . 1–2 . 50–7 . December 2011 . 21982618 . 10.1016/j.jns.2011.09.005. 9442941 .
  17. Web site: Multiple Sclerosis . Web.stanford.edu . 1997-03-21 . 2015-04-01.
  18. Web site: Dietary Changes in Temporal Relation to Multiple Sclerosis in the Faroe Islands : An Evaluation of Literary Sources . Klaus Lauer . While-science-sleeps.com . 2015-04-01.
  19. Lauer K . Some comments on the occurrence of multiple sclerosis in the Faroe Islands . Journal of Neurology . 233 . 3 . 171–3 . June 1986 . 3522812 . 10.1007/BF00314427. 22437259 .
  20. Lauer K . Multiple sclerosis in relation to industrial and commercial activities in the Faroe Islands . Neuroepidemiology . 7 . 4 . 228–33 . 1988 . 3264057 . 10.1159/000110155.
  21. Lauer K . Dietary changes in temporal relation to multiple sclerosis in the Faroe Islands: an evaluation of literary sources . Neuroepidemiology . 8 . 4 . 200–6 . 1989 . 2755551 . 10.1159/000110183.
  22. Web site: Maxmen . Amy . Amy Maxmen . Whodunit? | Multiple Sclerosis Discovery Forum . Msdiscovery.org . 2015-04-01.
  23. Lauer K . Environmental associations with the risk of multiple sclerosis: the contribution of ecological studies . Acta Neurologica Scandinavica. Supplementum . 161 . 77–88 . 1995 . 7653250 . 10.1111/j.1600-0404.1995.tb05861.x. 7159802 .
  24. Lauer K . Environmental risk factors in multiple sclerosis . Expert Review of Neurotherapeutics . 10 . 3 . 421–40 . March 2010 . 20187864 . 10.1586/ern.10.7. 20219149 .
  25. 3405364. 1988. Lauer. K. Sociogeographic factors and multiple sclerosis--an ecological study in 6 European countries. Neuroepidemiology. 7. 3. 122–9 . 10.1159/000110145.
  26. 2586701. 1989. Lauer. K. Multiple sclerosis in relation to meat preservation in France and Switzerland. Neuroepidemiology. 8. 6. 308–15 . 10.1159/000110199.
  27. A factor-analytical study of the multiple sclerosis mortality in Hesse and Baden-Wuerttemberg, Germany. 1993-12-01 . 10.1007/BF02959681 . 1 . 4 . Journal of Public Health . 319–327. Lauer. Klaus. 32460157 .
  28. 2402320. 1990. Lauer. K. Mortality of multiple sclerosis in relation to geographic factors in France. Neuroepidemiology. 9. 3. 113–7 . 10.1159/000110759.
  29. 2911392. 1989. Lauer. K. Risk of multiple sclerosis in relation to industrial activities: An ecological study in four European countries. Neuroepidemiology. 8. 1. 38–42 . 10.1159/000110163.
  30. 9017026. 1996. Gusev. E. Environmental risk factors in MS: A case-control study in Moscow. Acta Neurologica Scandinavica. 94. 6. 386–94. Boiko. A. Lauer. K. Riise. T. Deomina. T . 10.1111/j.1600-0404.1996.tb00050.x. 20421779. free.
  31. 8283194. 1994. Lauer. K. The risk of multiple sclerosis in the U.S.A. In relation to sociogeographic features: A factor-analytic study. Journal of Clinical Epidemiology. 47. 1. 43–8 . 10.1016/0895-4356(94)90032-9.
  32. Web site: Divergent risk of multiple sclerosis in two anabaptist communities in…. https://archive.today/20140804225814/http://www.medical-hypotheses.com/article/S0306-9877(06)00262-3/abstract . dead . 2014-08-04 .
  33. 17242346. 2007. Lauer. K. Alter. M.. Kahana. E.. Zilber. N.. Miller. A.. Multiple sclerosis frequency in Israel's diverse populations. Neurology. 68. 4. 311; author reply 311. 10.1212/01.wnl.0000255650.40828.98. 6452138.
  34. The food pattern in geographical relation to the risk of multiple sclerosis in the Mediterranean and Near East region . 2014-11-12 . 1060768 . 1757770 . 45 . 3 . J Epidemiol Community Health . 251–2 . Lauer K. 10.1136/jech.45.3.251 .
  35. Klaus Lauer . Diet and multiple sclerosis . Neurology . 49 . 2 Suppl 2 . S55–S61 . 1997-08-01 . 10.1212/WNL.49.2_Suppl_2.S55 . 9270693 . 5740619 .
  36. 1999685. 1991. Lauer. K. The history of nitrite in human nutrition: A contribution from German cookery books. Journal of Clinical Epidemiology. 44. 3. 261–4 . 10.1016/0895-4356(91)90037-a.
  37. Web site: Dr. Klaus Joachim Lauer Biography – Webcast powered by - MULTIWEBCAST - State-of-the-art Webcast Services . Multiwebcast.com . 2015-04-01.
  38. Klaus Lauer . Multiple sclerosis incidence in the Faroe Islands . Multiple Sclerosis Journal . 17 . 11 . 1393–1394 . 2011-06-13 . 10.1177/1352458511408479 . 21669934 . 39510239 .
  39. IJMS | Free Full-Text | Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits . International Journal of Molecular Sciences . 15 . 3 . 3533–3545 . 10.3390/ijms15033533 . 24577315 . 2014 . Lauer . Klaus . 3975352 . free .
  40. A questionnaire for multinational case-control studies of environmental risk factors in multiple sclerosis (EnvIMS-Q). 2012-12-20 . 10.1111/ane.12032 . 23278656 . 126 . 195 . Acta Neurologica Scandinavica . 43–50. Pugliatti. M.. Casetta . I. . Drulovic . J. . Granieri . E. . Holmøy . T. . Kampman . M. T. . Landtblom . A.-M. . Lauer . K. . Myhr . K.-M. . Parpinel . M. . Pekmezovic . T. . Riise . T. . Zhu . B. . Wolfson . C. . 29741160 . free .
  41. Sun exposure and multiple sclerosis risk in Norway and Italy: The EnvIMS study . Multiple Sclerosis Journal . 20 . 8 . 1042–1049 . 2014-01-10 . 10.1177/1352458513513968 . 24414538 . Bjørnevik . Kjetil . Riise . Trond . Casetta . Ilaria . Drulovic . Jelena . Granieri . Enrico . Holmøy . Trygve . Kampman . Margitta T. . Landtblom . Anne-Marie . Lauer . Klaus . Lossius . Andreas . Magalhaes . Sandra . Myhr . Kjell-Morten . Pekmezovic . Tatjana . Wesnes . Kristin . Wolfson . Christina . Pugliatti . Maura . 20910092 .
  42. Web site: Abstractverwaltung Congrex . Registration.akm.ch . 2013-10-03 . 2015-04-01 . https://web.archive.org/web/20140729181433/http://registration.akm.ch/einsicht.php?XNABSTRACT_ID=179808&XNSPRACHE_ID=2&XNKONGRESS_ID=195&XNMASKEN_ID=900 . 2014-07-29 . dead .
  43. 17623729. 2007. Sobocki. P. Estimation of the cost of MS in Europe: Extrapolations from a multinational cost study. Multiple Sclerosis. 13. 8. 1054–64. Pugliatti. M. Lauer. K. Kobelt. G. 10.1177/1352458507077941. 3263445.
  44. 9270687. 1997. Wolfson. C. Case-control studies in multiple sclerosis. Neurology. 49. 2 Suppl 2. S5–14. Granieri. E. Lauer. K. 10.1212/WNL.49.2_Suppl_2.S5. 31780484.
  45. 1575007. 1992. Riise. T. Early prognostic factors for disability in multiple sclerosis, a European multicenter study. Acta Neurologica Scandinavica. 85. 3. 212–8. Grønning. M. Fernández. O. Lauer. K. Midgard. R. Minderhoud. J. M.. Nyland. H. Pálffy. G. Poser. S. Aarli. J. A. . 10.1111/j.1600-0404.1992.tb04031.x. 44476. free.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Klaus Lauer".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.