| Klaserie River | |
| Pushpin Map: | South Africa |
| Pushpin Map Caption: | Location of the Klaserie River's mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | South Africa |
| Subdivision Type2: | State |
| Subdivision Name2: | Limpopo Province |
| Source1: | East of Blyde River Canyon |
| Source1 Coordinates: | -24.5572°N 30.9109°W |
| Mouth: | Olifants River, Limpopo |
| Mouth Location: | Kruger National Park |
| Mouth Coordinates: | -24.0821°N 31.2489°W |
The Klaserie River is a river in Limpopo Province, South Africa. It flows northeastwards and is a tributary of the Olifants River, joining it at 90° in the west of the Kruger National Park.