| Klaserie Game Reserve | |
| Photo Width: | 250 |
| Map: | South Africa |
| Relief: | yes |
| Map Width: | 250 |
| Location: | Limpopo, South Africa |
| Nearest City: | Hoedspruit |
| Coordinates: | -24.2578°N 31.2177°W |
| Area: | 60000ha |
| Url: | http://www.klaserie.co.za |
Klaserie Game Reserve is adjacent to the Kruger Park and the Timbavati Game Reserve, in the Limpopo province of South Africa. It has an area of about 60,000 ha and the Klaserie River runs through the park.
Wildlife species include lion, elephant, white rhinoceros, African leopard, southeast African cheetah, African wild dog, spotted hyena, Cape buffalo and many antelope species.