| Killer Creek | |
| Pushpin Map: | Canada Southern Ontario |
| Pushpin Map Caption: | Location of the mouth of Killer Creek in southern Ontario |
| Subdivision Type1: | Country |
| Subdivision Name1: | Canada |
| Subdivision Type2: | Province |
| Subdivision Name2: | Ontario |
| Subdivision Type3: | Region |
| Subdivision Name3: | Eastern Ontario |
| Subdivision Type4: | County |
| Subdivision Name4: | Lennox and Addington |
| Subdivision Type5: | Municipality |
| Subdivision Name5: | Addington Highlands |
| Length: | 10.4km (06.5miles) |
| Source1: | Unnamed lake |
| Source1 Coordinates: | 44.8883°N -77.3164°W |
| Source1 Elevation: | 344m (1,129feet) |
| Mouth: | Skootamatta Lake |
| Mouth Coordinates: | 44.8358°N -77.3131°W |
| Mouth Elevation: | 289m (948feet) |
| River System: | Great Lakes Basin |
Killer Creek is a creek in the Moira River and Lake Ontario drainage basins in Addington Highlands, Lennox and Addington County, Ontario, Canada.
Killer Creek begins at an unnamed lake at an elevation of 344m (1,129feet) and flows southwest to Killer Lake at an elevation of 328m (1,076feet). It then heads generally south to reach its mouth at the west end of Skootamatta Lake on the Skootamatta River at an elevation of 289m (948feet). The Skootamatta River flows via the Moira River to the Bay of Quinte on Lake Ontario at Belleville.